Using non-SLS On Guard Toothpaste while on medication

One of the things that really changed when I started taking Methotrexate is my choice in toothpaste. You see, Methotrexate is a drug used as chemotherapy (I use it to treat Psoriatic Arthritis) and can cause mouth sores (like canker sores). These mouth sores are easily aggravated and exacerbated when using a toothpaste that contains SLS (Sodium Lauryl Sulfate).  SLS can create those same canker sores!

Most toothpastes you find on the shelves at your local store contain this additive (that can also be found in industrial strength cleaning products! eek!). I was using one of those toothpastes before I started taking the medication but, after some research, decided I would never use a SLS-containing toothpaste again. It is scary to me that an industrial degreaser has the same additive as a toothpaste I am using.

So, why is it even being used in toothpaste? Well, it creates that foaming action everyone loves so much. I love it too so when I as searching for an alternative to an SLS toothpaste, I specifically looked for something that would give me what I am looking for… a clean feeling and performance.

There are several products available but the one that I decided to go with is the doTerra On
Guard Natural Whitening Toothpaste

doterra on guard toothpaste

doTERRA’s fluoride-free Natural Whitening Toothpaste combines the protective benefits of dōTERRA’s proprietary On Guard® blend of Certified Pure Therapeutic Grade essential oils with other natural ingredients that help strengthen teeth, reduce plaque and whiten teeth with gentle polishing agents. The On Guard® blend of wild orange, clove, cinnamon, eucalyptus, and rosemary essential oils provides a first line of defense against germs and other pathogens that can infect the mouth and throat. Additional essential oils of peppermint and wintergreen and the natural sweetener xylitol give On Guard Natural Whitening Toothpaste a refreshingly unique cinnamon-mint flavor leaving breath (and toothbrush) fresh and clean throughout the day.

The On Guard toothpaste cleans my mouth and teeth without using fluoride or alcohol, two ingredients that could cause problems in my already-sensitive mouth. On Guard Natural Whitening Toothpase includes calcium hydroxyapatite, a safe alternative to fluoride that helps strengthen dental enamel by restoring equilibrium of tooth remineralization. It also includes hydrated silica, a gentle abrasive that helps remove plaque and brighten teeth during brushing.

Key Ingredients

  • Proprietary On Guard® essential oil blend of wild orange, clove, cinnamon, eucalyptus, and rosemary that clean and freshen breath while providing natural protection against germs and other harmful microbes in the mouth
  • Myrrh essential oil that provides soothing protection for the mouth, gums, and throat
  • Peppermint essential oil that functions as a natural germ-fighting agent and, combined with the On Guard essential oil blend, leaves your breath cinnamon-mint fresh
  • Calcium hydroxyapatite clinically shown to support strong teeth through remineralization of surface tooth enamel
  • Natural xylitol sweetener that tastes great while promoting oral health
  • Hydrated silica, a natural abrasive that helps remove plaque and tooth stains, but gentle enough to not damage tooth enamel

I absolutely love how my teeth feel clean and my mouth feels fresh after using the On Guard toothpaste. With this, I feel safe knowing that the bacteria in my mouth is gone after brushing and I have noticed that my gums are looking better too. I used to have bleeding gums often but that is no longer a problem. I have NEVER had a canker sore since starting this toothpaste and that is a huge risk with the medication I am taking. Finally, I love the fresh breath I get when using this product.

So, for anyone who needs an SLS free toothpaste (those on chemotherapy or who suffer from mouth sores), I would highly recommend doTerra’s On Guard Natural Whitening Toothpaste. Even if you don’t have a specific need for this type of toothpaste, you really can’t go wrong with using it. I use a small dime-size amount and a tube lasts me a long time. Don’t hesitate to give it a try!

Don’t be fooled by off-brand essential oils! If you are putting them on or in your body, you want the purest form of them. Why not get the best? Are you interested in learning more about how doTerra essential oils can help you??  Email me at and I will be happy to answer any questions for you! You can order them directly HERE!

This post, as well as others on this website, are my true experiences. I am a distributor of the company simply to get the discounts and can help you with that if you want it. If you don’t think that doTerra is for you, please check out other sources. I just want you to get what you are comfortable with and doTerra was it for me.

The product statements on this website have not been evaluated by the Food and Drug Administration. doTERRA essential wellness products are not intended to diagnose, treat, cure, or prevent disease.


  1. Sandra says

    do you know of a dentist is recomending onaguard tooth paste to theire patiens?

  2. Tiffaney says

    I use this toothpaste, but SLS is listed on the product label…. Are you sure that yours does not include this item?

    • Tiffaney says

      I guess it is a different kind… Called Sodium Lauroyl Sarcosinate…. I just saw the acronym SLS and this name fits also, but is different…. Good to know! 😀

Leave a Reply

Your email address will not be published. Required fields are marked *